A glycosphingolipid that contains one or more residues of N-acetyl or other neuraminic acid derivatives. Gangliosides are found in highest concentration in cells of the nervous system, where they can constitute as much as 5% of the lipid.

Dictionary of molecular biology. 2004.

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  • Ganglioside — is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (e.g. n acetylneuraminic acid, NANA) linked on the sugar chain. The 60+ known gangliosides differ mainly in the position and number of NANA …   Wikipedia

  • ganglioside — [gɑ̃glijozid] n. m. ÉTYM. Mil. XXe; de ganglion, ose, et ide. ❖ ♦ Chim., biol. Ensemble des lipides renfermant du sucre (glycolipides), présents dans les ganglions du cerveau, et dont l accumulation dans les tissus de soutien de certains organes… …   Encyclopédie Universelle

  • Ganglioside — Ganglioside,   Singular Gangliosid das, s, Biochemie: Gruppe der Glykolipide …   Universal-Lexikon

  • ganglioside — [gaŋ′glēə sīd΄] n. [ GANGLI(O) + OSE1 + IDE] any of a group of complex lipids found mainly on the membranes of nervous tissue and in the liver, spleen, and kidney …   English World dictionary

  • Ganglioside — Struktur des GM1 Gangliosids Ganglioside [1][2][3][4] …   Deutsch Wikipedia

  • Ganglioside GM2 activator protein — is (GM2 AP) is a lipid transfer protein that stimulates the enzymatic processing of gangliosides, and also T cell activation through lipid presentation.This protein binds molecules of ganglioside GM2, extracts them from membranes, and presents… …   Wikipedia

  • Ganglioside galactosyltransferase — In enzymology, a ganglioside galactosyltransferase (EC number| is an enzyme that catalyzes the chemical reaction:UDP galactose + N acetyl D galactosaminyl (N acetylneuraminyl) D galactosyl 1,4 beta D glucosyl N acylsphingosine… …   Wikipedia

  • ganglioside GM1 — a ganglioside structurally similar to ganglioside GM2 but with an additional galactose residue linked to the N acetylgalactosamine residue of GM2; it accumulates abnormally in tissues in GM1 gangliosidoses …   Medical dictionary

  • ganglioside GM2 — a ganglioside containing an N acetylgalactosamine residue linked to the galactose of the core structure; it accumulates abnormally in tissues in GM2 gangliosidoses …   Medical dictionary

  • ganglioside — noun Etymology: International Scientific Vocabulary ganglion + 2 ose + ide Date: 1943 any of a group of glycolipids that yield a hexose sugar on hydrolysis and are found especially in the plasma membrane of cells of the gray matter …   New Collegiate Dictionary

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